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PhD., Applied Mechanics
California Institute
of Technology, Pasadena,
California, 2002.
M.S., Applied Mechanics
California Institute
of Technology, Pasadena,
California, 1998.
B.
Tech., Mechanical Engineering
Indian Institute of
Technology, New Delhi,
India, 1997.
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I am interested in problems
at the interface of mechanics,
physics and biology. The mechanics
of DNA is one such subject where
the Kirchhoff theory of filaments
can be used to describe not
just the behaviour of DNA at small scales but also
its implications on the life
cycle of viruses and the switching
on and off of genes. Understanding
the effects of thermal fluctuations
in this context is a major thrust
of my research. I am also interested
in biological applications of
the mechanics of lipid membranes
and the mechanics of material
interfaces in slender bodies.
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1.“Piezoelectric nanoribbons for monitoring cellular deformations”, Thanh D. Nguyen, Nikhil Deshmukh, John M. Nagarah, Tal Kramer, Prashant K. Purohit, Michael J. Berry, Michael C. McAlpine, To appear in Nature Nanotechnology, (2012).
2.“The dependence of DNA supercoiling on solution electrostatics”, David Argudo and Prashant K. Purohit, Acta Biomaterialia 8, 2133-2143, (2012).
3.“Semiflexible filament networks viewed as fluctuating beam frames”, Tianxiang Su and Prashant K. Purohit, Soft Matter 8(17), 4664-4674, (2012).
4.“Phase boundaries as agents of structural change in macromolecules”, Ritwik Raj and Prashant K. Purohit, J. Mech. Phys. Solids 59, 2044-2069, (2011).
5. "Transition between two regimes describing internal fluctuation of DNA in a nanochannel", Tianxiang Su, Somes K. Das, Ming Xiao, Prashant K. Purohit, PLoS One Vol. 6, e16890, (2011).
6.“Multiscale mechanics of fibrin polymer: Gel stretching with protein unfolding and loss of water”, Andre E. X. Brown, Rustem I, Litvinov, Dennis E. Discher, Prashant K. Purohit, John W. Weisel, Science Vol. 325. no. 5941, pp. 741 - 744, (2009).
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