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Name |
Thesis Title |
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Plasmid Delivery Mechanisms to Endothelium via RNA Interference |
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Systems Biology of Blood Coagulation and Platelet Activation |
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High-Throughput Screening (HTS) |
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Transport and biorheological effects in human coagulation |
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Systems modeling of calcium homeostasis and mobilization in platelets mediated by IP3 and store-operated calcium entry |
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William Denney |
High throughput blood experimentation and simulation |
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Characterization of cationic glucocorticoids as gene delivery, antimicrobial, and anti-inflammatory agents |
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Lattice kinetic Monte Carlo simulations of platelet aggregation and deposition |
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Interplay of ethanol and cholesterol in the neutrophil membrane: Effects on membrane and cell mechanics and neutrophil adhesion |
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Rachel Handwerger |
Photolabile Polyethylenimines for Light-Activated Nucleic Acid Delivery |
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A Microfluidic Approach for Investigating the Role of Blood Flow in Thrombosis |
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Pairwise platelet activation in flow cytometry |
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Development of Screening Platforms for Enhancing Production and Evaluation of Platelets Produced in vitro |
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Systems Biology of Platelet Activation |
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Microfluidic Approaches to Thrombosis and Hemostasis: A Global Investigation of Antiplatelet Therapeutics and the Assessment of Bleeding and Coagulopathy in Hemophilic and Trauma Patients |
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HTS Specialist |
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Multiscale Modelling of Platelet Aggregation |
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High-Throughput Screening (HTS) |
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Microfluidic focal injury models of thrombosis and hemostasis |
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Assay development and miniaturization; high-throughput screening (HTS) |
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Brian Murphy |
Optimization and analysis of single-stranded oligonucleotide directed gene targeting in mouse embryonic stem cells |
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A Microfluidic Approach for Investigating the Role of Intrathrombus Transport in Thrombosis and Hemostasis |
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Coordinating Gene Therapies of Cystic Fibrosis Airway Disease with Anti-Inflammatory and Antimicrobial Cationic Glucocorticoids |
 |
Andrew Napper |
Laboratory Director |
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|
A membrane-based microfluidic device for controlling the flux of platelet agonists into flowing blood |
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Ethanol and cholesterol effects on neutrophil adhesion: Mechanisms and pathophysiological implications |
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Human blood coagulation on matrix protein microarrays under venous and arterial flow |
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Development Of A High Throughput Assay To Optimize Hematopoietic Differentiation Of Human Pluripotent Stem Cells |
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Amber Price |
Dexamethasone -spermine as a local drug and gene delivery vehicle for improved pulmonary gene therapy |
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A systems approach to cellular signal transduction |
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A series of cationic sterol lipids with gene transfer, bactericidal and anti-endotoxin activity |
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Protease HTS and coagulation |
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Protease inhibitor development and substrate specificity profiling |
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Coupling molecular dynamics with lattice Boltzmann method based on immersed boundary method |
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High throughput screening for the enhancement of adeno-associated virus type 2 transduction |
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Discovery and characterization of novel inhibitors against cathepsin L and exploring their potential as anti Ebola/ SARS virus infection therapeutics |
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A systems approach to hemostasis: how the feedback between thrombus structure and molecular transport regulate the hemostatic response |
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Advancing microarrays with acoustic dispensing technology and probing the kinome |
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A Microfluidic Approach for Evaluating Novel Antithrombotic Targets |
| |
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Institute of Medicine & Engineering (IME)
